Since 2008 Prof. Crea is Professor of Cardiology, Director of the Department of Cardiovascular Sciences, Director of the Postgraduate School in Cardiology and Coordinator of the PhD program in Cellular and Molecular Cardiology at the Catholic University in Rome. Research activity has been mainly focused on the study of the multiple mechanisms of myocardial ischemia in chronic and acute coronary syndromes. Prof. Crea has been awarded numerous research awards including the Arrigo Recordati International Prize for the “Lifetime achievement in researching the pivotal role of microcirculation in systemic and organ diseases”. He has given prestigious lectureship worldwide including the 7th annual Robert L. Krakoff International Lecture in Cardiovascular Medicine at the Brigham and Women’s Hospital, Harvard University Medical School. Since September 2020 he is Editor-in-Chief of the European Heart Journal.